Congenital CMV

Congenital CMV infection – a problem ignored?

July 5th, 2017

Congenital CMV infection – a serious problem that receives little attention Cytomegalovirus (CMV) is a human specific double stranded DNA virus, belonging to the Herpesviridae family. CMV is ubiquitous and CMV infection is globally widespread. The virus can be transmitted through direct contact with infected bodily fluids or though contact with virus infected transplant and […]

yellow fever virus

Yellow Fever Virus continues its resurgence

July 5th, 2017

In January 2017, the World Health Organization (WHO) reported an increase in the number of cases of yellow fever in the Minas Gerais state of Brazil, and the states of Espirito Santo and Sao Paulo (1,2). Since January, human and epizootic cases of yellow fever have been reported in the neighbouring State of Bahia. Attempts […]

The Native Antigen Company supports R&D on emerging diseases

May 14th, 2017

The WHO Priority list of emerging diseases In 2015, a group of public health and science experts gathered in Geneva to discuss emerging pathogens, that cause human disease (1). Organised by the WHO, their aim was to prioritise infectious diseases which are likely to cause a severe epidemic and which could present a public health […]

Zika virus envelope protein – another chapter of the ZIKV story

May 5th, 2017

  Zika virus (ZIKV) is an enveloped single stranded RNA virus. It is a member of the Flavivirus genus of the family Flaviviridae which also includes the global human pathogenic viruses Dengue virus (DENV), Yellow Fever virus (YFV), West Nile virus (WNV) and Japanese encephalitis virus (JEV). Zika virus recently emerged from obscurity during a […]

Humanised antibodies as serological controls for Zika virus diagnostics

March 30th, 2017

Unique humanised antibodies engineered for use as serological controls for Zika diagnostics Serological testing is central to the diagnosis of acute and past viral infections. This is undertaken by detecting levels of anti-viral IgM or IgG antibodies in the sera of infected patients. The detection of specific anti-viral IgM is indicative of an acute or […]

Ongoing challenges for Zika diagnostics

January 19th, 2017

Continuing challenges for Zika virus diagnostics as we move into 2017 Although the formal Public Health Emergency for Zika virus infection has been declared over, the virus continues to present major challenges to global healthcare networks. The virus continues to spread to new areas, having been reported for the first time in Texas and also […]

Yellow Fever outbreaks cause worldwide concern

June 3rd, 2016

Yellow Fever outbreaks cause worldwide concern Whilst much of the world focuses its attention on the outbreak of Zika virus in South America, scientists and public health officials are becoming increasingly concerned about the resurgence of Yellow Fever in parts of Africa, which they believe may have the potential to spread as far afield as […]

Zika Virus TEM

Zika virus spreads across the Americas

January 28th, 2016

The emergence of “new” viruses has long been a concern in the popular press and even in Hollywood.  However, in the last few years a certain amount of reality has followed the hype.  In addition to the epidemic of Ebola in Africa in 2014/5, which killed more than 10,000 people, viruses such as Dengue, West […]

CMV vaccine progress

CMV vaccine progress – the gH pentamer story

September 4th, 2015

CMV vaccine progress – the gH pentamer story What is CMV? Human cytomegalovirus (HCMV) is a member of the β-herpesviruses. It is a global, species-specific, highly successful pathogen with a seroprevalence of 50-90%, depending on socio-economic status (1). The virus can be transmitted both vertically and horizontally by bodily fluids, establishing a life-long latent infection […]

brown cows

Dengue NS1 apolipoprotein interaction revealed

July 28th, 2015

Dengue Virus NS1 apolipoprotein interaction described A Dengue Virus NS1 apolipoprotein co-purification has been observed by Native Antigen Company scientists, with possible important consequences for NS1 research. Scientists at The Native Antigen Company discovered during research on optimal expression methods that dengue virus NS1, recombinantly expressed in cells cultured in foetal bovine serum (FBS) and […]