Purified Hantavirus antibodies supplied by The Native Antigen Company are suitable for immunoassay research and development.
Hantaviruses (HTNV) belong to the Hantavirus genus within the family Bunyaviridae. Hantaviruses are zoonotic pathogens that have global distribution. Rodents and small mammals act as natural reservoirs for Hantaviruses but remain asymptomatic after infection. Airborne transmission of hantaviruses to humans occurs via inhalation of dust or aerosols contaminated by urine, saliva or droppings from infected animals.In humans, hantaviruses cause two acute febrile disease syndromes, haemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). HFRS and HCPS are caused by different strains of hantavirus. HCPS is predominantly caused by the Sin Nombre strain of hantavirus, which is distributed throughout North, Central and South America. The symptoms of HCPS are characterised by fever, fatigue, muscle ache, headaches, nausea, vomiting and non-cardiogenic pulmonary oedema. HCPS can be fatal in 38% of reported cases
Hantavirus strains that cause HFRS are endemic in Europe and Asia. The strains of HTNV involved in HFRS are referred to as Old World hantaviruses and include Hantaan, Dobrava, Saaremaa, Seoul and Puumala. The clinical symptoms associated with HFRS include fever, renal dysfunction, thrombocytopenia, haemorrhage and shock (CDC). HFRS can be fatal in 1-15% of cases.
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