Our Influenza antibodies are suitable for use in immunoassay research and development.
Influenza viruses are enveloped, segmented, negative-sense, single-stranded RNA viruses of the Orthomyxoviridae family. There are three major antigenic types of influenza that are clinically relevant to humans. These are classified as influenza A, B and C. Influenza A viruses affect humans and bird populations, whilst influenza B and C only infect humans. Influenza A viruses are the most virulent human pathogens among the three influenza types and are the predominant cause of seasonal and pandemic influenza (Bouvier, NM).
Influenza A viruses are further divided into subtypes based on the expression and combination of two envelope glycoproteins called haemagglutinin (H, also referred to as HA) and neuraminidase (N), which are important targets for the immune system. Influenza A viruses undergo high rates of mutation and gene rearrangement which lead to antigenic variations of these glycoproteins. There are 18 H subtypes and 11 N subtypes recognised to date (CDC). The subtypes currently circulating among the human population are influenza A(H1N1) and influenza A(H3N2) (WHO).
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