3CD16a/Fcgr3A, C-terminal Avi-HIS-tag, in vivo biotinylated

$326.43 – $1,171.80 excl. VAT

Soluble CD16A/Fcgr3a, C-terminally HIS-Avi-tagged, produced in HEK293 cells and in vivo mono-biotinylated. Recombinant FcγRs can be used to monitor immune processes, providing a time-efficient and reproducible alternative to laborious cell-based assays.

3CD16a/Fcgr3A, C-terminal Avi-HIS-tag, in vivo biotinylated

Soluble CD16A/Fcgr3a, C-terminally HIS-Avi-tagged, produced in HEK293 cells and in vivo mono-biotinylated. Recombinant FcγRs can be applied in multiplex assays to characterise IgG subclass-specific affinities supporting research into immune therapies, including therapeutic antibodies and novel vaccines.

PRODUCT DETAILS – 3CD16a/Fcgr3A , C-terminal Avi-HIS-tag, in vivo biotinylated

Recombinant human 3CD16a/Fcgr3A protein, in vivo biotinylated
Proteins contain a C-terminal Avi-HIS-tag
NCBI Accession number: P08637-1
Proteins were expressed in HEK293 cells and purified from culture supernatant by immobilised metal affinity chromatography.
Presented as Liquid

Useful links

Junker, F., Gordon, J. and Qureshi, O. (2020) “FC gamma receptors and their role in antigen uptake, presentation, and T cell activation,” Frontiers in Immunology, 11. Available at: https://doi.org/10.3389/fimmu.2020.01393.

Nath, N. et al. (2022) “A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptors,” Scientific Reports, 12(1). Available at: https://doi.org/10.1038/s41598-022-15887-z.