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Renibacterium Salmoninarum

Renibacterium salmoninarum is a bacterium that causes Bacterial Kidney Disease (BKD) in salmonid fish. BKD is usually a chronic disease and causes mortality in juvenile fish and pre-spawning adults. Due to its prevalence, it has a significant impact upon both farmed fish and conservation efforts in wild endangered species.

Renibacterium Salmoninarum Background

Renibacterium salmoninarum is a gram positive, diplobacillus, rod shaped, non-motile, non spore forming intracellular bacterium that causes Bacterial Kidney Disease (BKD) in salmonid fish. BKD is usually a chronic disease and causes mortality in juvenile fish and pre-spawning adults. Due to its prevalence, it has a significant impact upon both farmed fish and conservation efforts in wild endangered species. It is the only species in the genus and its production of chronic granulomata within the tissues is similar to that caused by Mycobacteria spp. in mammals.

This disease is present in North America, UK, Continental Europe, Japan, Chile and Scandinavia. It can be spread horizontally via shared water and vertically. Horizontal transmission is likely the result of ingestion of faecal materials from clinical infected and/or carrier fish. Vertical transmission via the egg makes is unusual for a bacterial pathogen. Most outbreaks have occurred in fish culture facilities. As the bacteria are often enzootic in wild populations and waterborne, transmission to captive fish is often a concern. Salmonids of the Onchorhynchus, Salmo and Salvelinus genera appear to be the primary hosts although many other species can acquire natural infections. The organism is highly adapted to both infectivity and persistence in these hosts. Its intracellular nature provides it with both a nutrient source and method of evasion from the host immune response. Pacific salmon species are the most susceptible with losses as high as 80% recorded, while Atlantic salmon and rainbow trout are thought to be more resistant.

References

  • Evelyn, T. P. T (1993) Bacterial kidney disease – BKD. In: Inglis, V., Roberts, R. J., Bromage, N.R. eds. Bacterial Diseases of Fish. New York, USA: Halsted Press, 177-195.

Renibacterium Salmoninarum Antigens

The Native Antigen Company is pleased to offer the Renibacterium BacTrace range of matching antibody and antigens which are suitable for diagnostic assay development and vaccine research.

Renibacterium Salmoninarum Antibodies

The Native Antigen Company is pleased to offer the Renibacterium BacTrace range of matching antibody and antigens which are suitable for diagnostic assay development and vaccine research.

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