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Welcome to The Native Antigen Company

World leading infectious disease reagents from the experts. Whether you need cutting edge reagents for your research or bulk products for manufacturing we can support all of your needs.

MXRA8 - The Alphavirus receptor

MXRA8 has recently been shown to be a viral entry receptor for Chikungunya and related viruses. We are pleased to release mammalian expressed recombinant MXRA8, to facilitate research into potential therapeutic options for blocking viral entry

Zika total antibody immunoassay

Our new ELISA assay for detecting serological responses to Zika has a novel format, excellent specificity and sensitivity, and an assay time of less than 2 hours! It’s also suitable for measuring Zika responses in any species, so perfect for animal model studies.

Mammalian protein expression services

Our proprietary mammalian expression system uses HEK293 cells in suspension culture. If you need a protein with high purity, with proper glycosylation and folding, our contract services may be exactly what you need.

About The Native Antigen Company

The Native Antigen Company (NAC) specialise in the development and manufacture of native and recombinant viral and bacterial antigens, antibodies and immunoassays. Our antigens are used by leading pharmaceutical companies and IVD manufacturers in vaccine research and serology where proper folding and glycosylation are vital. As well as offering antigens from a rapidly expanding portfolio, NAC now offers an increasing range of highly specific antibodies and ELISA immunoassays. Our expertise is also available to customers on a contract basis for those needing custom protein manufacture in our proprietary mammalian cell protein expression system, together with antibody and immunoassay development.

Antigens

We produce infectious disease antigens from a range of established and emerging viral, bacterial and protozoal diseases. We provide both native antigens and recombinant antigens produced using our mammalian expression system. Our antigens are suitable for use in vaccine R&D, as components for serological based diagnostic assays and for fundamental research into infectious disease. We have many years of experience in providing bulk and customised formats for industry – contact us to discuss your needs.

Antibodies

We aim to develop the world’s most extensive range of antibodies for infectious disease targets, and are rapidly expanding our current range. Our range includes a unique panel of highly specific antibodies for flavivirus NS1 proteins, including serotype specific reagents for Dengue and human chimeric antibodies to Zika NS1. Check back regularly to see the latest additions.

Immunoassays

Our immunoassays for Zika virus are the most specific and sensitive available on the market. We have assays to detect the serological response to infection, and also to measure levels of Zika NS1 protein during infecton.

Contract and Custom services

With a foundation of decades of experience in the field of native antigen and recombinant protein contract research, process development and production, NAC is able to undertake custom projects to manufacture your proteins and antigens, prepare antibodies and develop immunoassays. Our development laboratories are fully staffed by a team of PhD molecular biologists and development scientists who are able to execute projects as short as a few days through to long term programmes of a year or more.

How The Native Antigen Company responds to the WHO list of priority infectious diseases

In 2015, a broad group of public health and science experts gathered in Geneva to discuss emerging infectious diseases that are likely to cause future severe epidemics and public health emergencies. Organised by the World Health Organization (WHO), their aim was to...

Native Antigen release a panel of serotype specific monoclonal antibodies

  There are four distinct serotypes of Dengue Virus circulating around the world, causing Dengue fever infection which is the most important worldwide arboviral disease. There are nearly 400 million cases of Dengue annually, and around 25% present with so called...

A silver-lining from Zika virus?

Zika virus (ZIKV) is an enveloped single stranded RNA virus. It is a member of the Flavivirus genus of the family Flaviviridae, which is transmitted to humans primarily through the bite of the Aedes aegypti mosquito. In 2015, a major outbreak of Zika virus was...

Congenital CMV – a problem ignored?

Congenital CMV infection – a serious problem that receives little attention Cytomegalovirus (CMV) is a human specific double stranded DNA virus, belonging to the Herpesviridae family. CMV is ubiquitous and CMV infection is globally widespread. The virus can be...

New Nipah Virus antigens now available from The Native Antigen Company

Infection with Nipah Virus (NiV) was first recognised in Malaysia 1998/1999, where a major outbreak occurred in pigs and humans. NiV infection is now endemic in South Asia and several outbreaks of NiV infection have been reported in India and Bangladesh. Currently an...

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