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Welcome to The Native Antigen Company

World leading infectious disease reagents from the experts

Whether you need cutting-edge reagents for your research or bulk products for manufacturing we can support your needs

Antigens, Antibodies, Immunoassays

 

We specialise in the development and manufacture of antigens, antibodies and immunoassays for viral and bacterial pathogens. We produce both native and recombinant antigens using our proprietary mammalian system and have decades of experience in bulk and scale production.

Custom and Contract Research Services

 

We can undertake custom projects to manufacture antigens and other proteins, prepare antibodies and develop immunoassays to support your R&D. Our development laboratories are fully staffed by a team of PhD molecular biologists and development scientists who are able to execute projects as short as a few days, through to long-term programmes of a year or more.

MXRA8 Receptor

Borrelia Antigens, Antibodies and Immunoassays

We now offer an extensive range of Borrelia burgdorferi antigens, antibodies and immunoassays. Our high-quality products are suitable for a range of laboratory research and vaccine development applications.

Zika Immunoassay Kit

Native Viral Lysates

We now offer an extensive range of lysates from a variety of virus strains to complement our highly pure native and recombinant antigens. These lysates contain a variety of native antigenic proteins and are able to elicit unique immune responses.

Mammalian-Expressed Proteins

Using Adenoviruses to Fight Cancer

Adenoviruses are one of the major contenders for a new generation of oncolytic gene therapy vectors to treat cancer. In the second of a 2-part series, we discuss how adenoviruses are being developed as cancer therapeutics and some of the hurdles these platforms face from our own immune systems.

About The Native Antigen Company

 The Native Antigen Company specialises in the development and manufacture of native and recombinant viral and bacterial antigens, antibodies and immunoassays, as well as bespoke product development and custom manufacturing. The company has decades of experience in producing high-quality proteins with its proprietary mammalian cell expression system to ensure correct glycosylation and proper folding. The Native Antigen Company’s high-quality reagents are widely adopted by leading pharmaceutical, in vitro diagnostic assay manufacturers, and academic groups in cutting-edge vaccine research and serology, where correct folding and glycosylation are vital.

The world’s most extensive range of NS1-specific antibodies for flavivirus research

The Native Antigen Company first gained prominence in 2016, when it developed highly pure Zika virus NS1 protein during the 2015/2016 epidemic. Since then, the company has developed an extensive range of highly specific antigens, antibodies and immunoassays for...

Flavivirus NS1: A Short Introduction

In the first of a two-part series, we describe the structure of Flavivirus Non-Structural Protein 1 (NS1) and the role that it plays in viral pathogenesis. Flavivirus proteins Flaviviruses are single-stranded, enveloped RNA viruses, belonging to the Flaviviridae...

Paper Synopsis: ELISA formats and antibody quenching to reduce ZIKV cross-reactivity

While the 2015/16 Zika epidemic no longer makes the headlines, there remains a crucial need to accurately and reliably diagnose Zika virus (ZIKV) infection to identify and manage further outbreaks. However, high levels of cross-reactivity among cocirculating...

Viral Lysates for Diagnostic Research

We've recently expanded our range of native viral cell lysates to complement our highly pure recombinant antigens. Here, we explain how our lysates are made and their uses in infectious disease R&D.What are viral lysates? Put simply, viral lysates are extracts of...

Cellular Receptors for Viral Entry

The most crucial step for viruses during human infection is recognition and entry into host cells. For this to happen, specific proteins on the virus capsid interact with those on the host cells' surface, through a 'lock-and-key'-type mechanism that mediates...

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