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Seasonal Influenza Vaccine Antigens

In February and September of each year, the World Health Organization (WHO) convenes with its network of advisors to decide on flu vaccine formulations for the northern and southern hemispheres, respectively. To support ongoing vaccine reformulation programmes, The Native Antigen Company develops season-specific antigens to support vaccine and diagnostic manufacturers.

Our Antigens

To support vaccine research and development, The Native Antigen Company has developed Haemagglutinin (HA) and Neuraminidase (NA) antigens for the WHO-recommended egg-based and recombinant vaccine strains. Available in bulk quantities, antigens can be used in a range of applications, including immunoassay development and as immunogens.

Expressed from our proprietary VirtuE™ HEK293 expression system, these antigens exhibit proper glycosylation and folding. Our latest Haemagglutinin antigens feature C-terminal T4 foldon domains, stabilising them in their trimeric conformation to present more native-like conformational epitopes.

For more information on our influenza products, click on the product codes below:

2023 Southern Hemisphere Flu Season Antigens

Species
Strain/Subtype
Antigen
GISAID No.
Product Code
 
Influenza A
 
 
A/Darwin/6/2021 (H3N2)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1885401
 
 
REC32021 >>>
 
 
A/Darwin/6/2021 (H3N2)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1885402
 
 
REC32037 >>>
 
 
A/Darwin/9/2021 (H3N2)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1859995
 
 
REC32003 >>>
 
 
A/Darwin/9/2021 (H3N2)-like virus
 
 
Hemagglutinin (HA)
 
 
EPI1859996
 
 
REC32002 >>>
 
 
A/Sydney/5/2021 (H1N1)pdm09-like virus
 
 
Neuraminidase (NA)
 
 
EPI1942221
 
 
REC32040 >>>
 
 
A/Sydney/5/2021 (H1N1)pdm09-like virus
 
 
Hemagglutinin (HA)
 
 
EPI1942222
 
 
REC32038 >>>
 
 
A/Wisconsin/588/2019 (H1N1)pdm09-like virus
 
 
Neuraminidase (NA)
 
 
EPI1957292
 
 
REC32040 >>>
 
 
A/Sydney/5/2021 (H1N1)pdm09-like virus
 
 
Hemagglutinin (HA)
 
 
EPI1957293
 
 
REC32039 >>>
 
 
Influenza B
 
 
B/Austria/1359417/2021
 
 
Haemagglutinin (HA)
 
 
EPI1857129
 
 
REC32004 >>>
 
 
B/Austria/1359417/2021
 
 
Neuraminidase (NA)
 
 
EPI1857130
 
 
REC32005 >>>
 
 
B/Austria/1359417/2021 (B/Victoria lineage)-like virus
 
 
Haemagglutinin (HA)
 
 
EPI1845793
 
 
REC32004 >>>
 
 
B/Austria/1359417/2021 (B/Victoria lineage)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1845794
 
 
REC32005 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1857129
 
 
REC31955 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
 
 
Hemagglutinin (HA)
 
 
EPI529345
 
 
REC32022 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
 
 
Neuraminidase (NA)
 
 
EPI551296
 
 
REC31955 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
 
 
Hemagglutinin (HA)
 
 
EPI551297
 
 
REC32022 >>>
 
 
A/Darwin/6/2021 (H3N2)-like virus
 
 
Neuraminidase (NA)
 
 
EPI1885401
 
 
REC32021 >>>
 

2022 Southern Hemisphere Flu Season Antigens

Species
Strain/Subtype
Antigen
Product Code
 
Influenza A
 
 
A/Wisconsin/588/2019 (H1N1)pdm09-like virus
 
 
Haemagglutinin (HA)
 
 
REC31200 >>>
 
 
A/Wisconsin/588/2019 (H1N1)pdm09-like virus
 
 
Neuraminidase (NA)
 
 
REC32001 >>>
 
 
A/Darwin/9/2021(H3N2)-like virus
 
 
Haemagglutinin (HA)
 
 
REC32002 >>>
 
 
A/Darwin/9/2021(H3N2)-like virus
 
 
Neuraminidase (NA)
 
 
REC32003 >>>
 
 
Influenza B
 
 
B/Austria/1359417/2021 (B/Victoria lineage)-like virus
 
 
Haemagglutinin (HA)
 
 
REC32004 >>>
 
 
B/Austria/1359417/2021 (B/Victoria lineage)-like virus
 
 
Neuraminidase (NA)
 
 
REC32005 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata Lineage)-like virus
 
 
Haemagglutinin (HA)
 
 
REC31954 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata Lineage)-like virus
 
 
Neuraminidase (NA)
 
 
REC31955 >>>
 

2021-2022 Northern Hemisphere Flu Season Antigens

Species
Strain/Subtype
Antigen
Product Code
 
Influenza A
 
 
A/Victoria/2570/2019 (H1N1)pdm09-Like
 
 
Haemagglutinin (HA)
 
 
REC31949 >>>
 
 
A/Victoria/2570/2019 (H1N1)pdm09-Like
 
 
Neuraminidase (NA)
 
 
REC31950 >>>
 
 
A/Cambodia/e0826360/2020 (H3N2)-Like
 
 
Haemagglutinin (HA)
 
 
REC31951 >>>
 
 
A/Cambodia/e0826360/2020 (H3N2)-Like
 
 
Neuraminidase (NA)
 
 
REC31952 >>>
 
 
Influenza B
 
 
B/Washington/02/2019 (B/Victoria lineage)-Like
 
 
Haemagglutinin (HA)
 
 
REC31888 >>>
 
 
B/Washington/02/2019 (B/Victoria lineage)-Like
 
 
Neuraminidase (NA)
 
 
REC31889 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata Lineage)-Like
 
 
Haemagglutinin (HA)
 
 
REC31954 >>>
 
 
B/Phuket/3073/2013 (B/Yamagata Lineage)-Like
 
 
Neuraminidase (NA)
 
 
REC31955 >>>
 

Our Influenza Products

We also offer an extensive range of recombinant HA/NA antigens, native cell lysates and species-specific monoclonal antibodies for established strains.

Our Influenza Services

To support influenza vaccine development, The Native Antigen Company also offers custom services to rapidly develop panels of high quality influenza antigens.

For a bespoke proposal and consultation, please get in touch using the form below

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