We have developed an extensive range of products for infectious disease research and development, and particularly for use in the manufacturing of immunoassays in the IVD sector, and for vaccine research in the biopharmaceutical sector.
The Native Antigen Company produces infectious disease antigens from a range of established and emerging viral, bacterial and protozoal diseases. We provide both native and recombinant antigens produced using our VirtuE, mammalian expression system. Our antigens are suitable for use in vaccine R&D, as components for serological based diagnostic assays and for fundamental research into infectious diseases. We have decades of experience in providing bulk and customised formats for industry.
We are working to develop the world’s most extensive range of antibodies for infectious disease targets, with a rapidly expanding range. Our range includes a unique panel of highly specific antibodies for flavivirus NS1 proteins, including serotype-specific reagents for Dengue and human chimeric antibodies to Zika NS1. We also offer a range of antibody pairs optimised for Capture and Detection, self pairing antibodies (Self Pair) and those which have been shown to pair but have not been fully optimised (Pair).
The Native Antigen Company offers a range of highly purified bacterial toxins that are widely used in cell biology applications, studying pathways in diseases such as cardiovascular disorders, cancer and diabetes. Pertussis toxin acts to inhibit the ability of G proteins to function in signalling pathways, whilst Diphtheria toxin inhibits protein synthesis by catalyzing ADP-ribosylation of eukaryotic aminoacyltransferase. In contrast Clostridium difficile toxins A and B act to destroy the actin cytoskeleton of cells by inactivation of Rho family GTPases. Each of our toxins are purified directly from cultured bacteria, and undergo several purification steps to produce highly pure reagents. The reagents are suitable for use in cellular assays, as antigens for antibody production, and also for use in IVD assays.
The Native Antigen Company now offers an expanding range of antigens, antibodies and immunoassays for companion animals and livestock.
We offer a range of accessory reagents to support the use of our antigens and antibodies, including disease-state donor sera, buffers, secondary antibodies and isotype control antibodies.