References
There is no better testament to the quality of a product than its citation in a peer-reviewed scientific publication. We aim to collate all of the references that we’re aware of below, but if you know of any others please do let us know. If you publish your own work and include a reference to one of our products, we will be pleased to offer you a 25% discount on your next order – just contact us for details.
Ad-GFP (available on request)
Mlcochova, P. et al. (2017). DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages. EMBO J. Oct 30. pii: e201796880. PMID: 29084722
Mo, S. et al. (2015). Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours. J Control Release. 210:10-8. PMID: 25975831
Ad-LUC (available on request)
Myers, R. et al. (2018). Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines. Int J Nanomedicine. Jan 10;13:337-349. PMID: 9391793
Sanders, T. et al. (2020). Investigating the Effect of Encapsulation Processing Parameters on the Viability of Therapeutic Viruses in Electrospraying. Pharmaceutics. Apr 24;12(4). pii: E388. PMID: 32344667
Ad5-MyoD (available on request)
Adkin, CF. et al. (2012). Multiple exon skipping strategies to by-pass dystrophin mutations. Neuromuscul Disord. Apr;22(4):297-305. PMID: 22182525
Aung-Htut, M. et al. (2020). Splice modulating antisense oligonucleotides restore some acidalpha-glucosidase activity in cells derived from patients with lateonset Pompe disease. Sci Rep. Apr 21;10(1):6702. PMID: 32317649.
Greer, K. et al. (2015). Pseudoexon activation increases phenotype severity in a Becker muscular dystrophy patient. Mol Genet Genomic Med. 3(4):320-6. PMID: 26247048
Greer, KL. et al. (2014). Targeted exon skipping to correct exon duplications in the dystrophin gene. Mol Ther Nucleic Acids. Mar 18;3:e155. PMID: 24643206
Fletcher, S. et al. (2013). Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. Sep;1(3):162-73. PMID: 24498612
Fletcher, S. et al. (2012). Targeted exon skipping to address “leaky” mutations in the dystrophin gene. Mol Ther Nucleic Acids. Oct 16;1:e48. PMID: 23344648
Toh, ZY. et al. (2016). Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS One. Jan 8;11(1):e0145620. PMID: 26745801
Zaric, M. et al. (2017). Long-lived tissue resident HIV-1 specific memory CD8+ T cells are generated by skin immunization with live virus vectored microneedle arrays. J Control Release. Dec 28;268:166-175. PMID: 29056444
Adenovirus Contract Manufacturing
Bachy, V. et al. (2013). Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays. Proc Natl Acad Sci U S A. Feb 19;110(8):3041-6. PMID: 23386724
Becker, PD. et al. (2015). Skin vaccination with live virus vectored microneedle arrays induce long lived CD8(+) T cell memory. Vaccine. Sep 8;33(37):4691-8. PMID: 25917679
O’Brien, LM. et al. (2014). Vaccination with recombinant adenoviruses expressing Ebola virus glycoprotein elicits protection in the interferon alpha/beta receptor knock-out mouse. Virology. Mar;452-453:324-33. PMID: 24461913
Zaric, M. et al. (2019) Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8+ effector recruitment to mucosal tissues. Nat. Comms. 10:2214
Adenoviruses 3, 5 and 11 (available on request)
Dyer, A. et al. (2016). Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Mol Ther Oncolytics. Dec 10;4:18-30. PMID: 28345021
Thoma, C. et al. (2013). Adenovirus serotype 11 causes less long-term intraperitoneal inflammation than serotype 5: implications for ovarian cancer therapy. Virology. Dec;447(1-2):74-83. PMID: 24210101
Adenovirus 40
Rosado, J. et al. (2021). Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study. Lancet Microbe. 2021 Feb;2(2):e60-e69. PMID: 33521709.
Pertussis Toxin
Doronin, VB. et al. (2016). Changes in different parameters, lymphocyte proliferation and hematopoietic progenitor colony formation in EAE mice treated with myelin oligodendrocyte glycoprotein. J Cell Mol Med. Jan;20(1):81-94. PMID: 26493273
Salcedo-Rivillas, C. et al. (2014). Pertussis toxin improves immune responses to a combined pneumococcal antigen and leads to enhanced protection against Streptococcus pneumoniae. Clin Vaccine Immunol. Jul;21(7):972-81. PMID: 24807055
Sanchis, P. et al. (2020). Interleukin-6 Derived From the Central Nervous System May Influence the Pathogenesis of Experimental Autoimmune Encephalomyelitis in a Cell-Dependent Manner. Cells. Jan, 9(2). PMID: 32023844
Tolmacheva, AS. et al. (2020). Increase in Autoantibodies-Abzymes with Peroxidase and Oxidoreductase Activities in Experimental Autoimmune Encephalomyelitis Mice during the Development of EAE Pathology. Molecules 2021, 26(7), 2077.
Filamentous Haemagglutinin
Pathirana, J. et al. (2021). Effect of cytomegalovirus infection on humoral immune responses to select vaccines administered during infancy. Vaccine. 2021 Aug 9;39(34):4793-4799. PMID: 34275675.
CHIKV VLP
Awadalkareem, A. (2021). Optimized production and immunogenicity of an insect virus-based chikungunya virus candidate vaccine in cell culture and animal models. PMID: 33539255.
Awadalkareem, A. (2021). A genetically stable Zika virus vaccine candidate protects mice against virus infection and vertical transmission. PMID: 33597526.
Dora, EG. (2019). An adjuvanted adenovirus 5-based vaccine elicits neutralizing antibodies and protects mice against chikungunya virus-induced footpad swelling. Vaccine. May, 37(24), 3146-3150. PMID: 31047675
Liu, JL. et al. (2020). Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody. Front Med (Lausanne). Jan 28;8:626028. PMID: 33585527
Liu, JL. et al. (2019). Selection and Characterization of Protective Anti-Chikungunya Virus Single Domain Antibodies. Molecular Immunology. PMID: 30550981
Liu, JL. et al. (2018). Selection of Single-Domain Antibodies Towards Western Equine Encephalitis Virus. Antibodies. PMID: 3154489
CHIKV Capsid
Troost-Kind, B. et al. (2021). Tomatidine reduces Chikungunya virus progeny release by controlling viral protein expression. PMID: 34762680.
CHIKV Envelope
Islamuddin, M. et al. (2021). Inhibition of Chikungunya Virus Infection by 4-Hydroxy-1-Methyl-3-(3-morpholinopropanoyl)quinoline-2(1H)-one (QVIR) Targeting nsP2 and E2 Proteins. ACS.
Liu, JL. et al. (2020). Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody. Front Med (Lausanne). Jan 28;8:626028. PMID: 33585527
Liu, JL. et al. (2018). Selection of Single-Domain Antibodies Towards Western Equine Encephalitis Virus. Antibodies.
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Seiler, BT. (2019). Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000 Research. PMID: 31275563.
Ushijima, Y. et al. (2021). Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections. BMC Infect Dis. 2021 Mar 17;21(1):265. PMID: 33731022.
CHIKV Lysate
Ganganboina, AB. et al. (2021). Cargo encapsulated hepatitis E virus-like particles for anti-HEV antibody detection. Biosens Bioelectron. 2021 Aug 1;185:113261. PMID: 33962156
Nasrin, F. et al. (2021). Design and Analysis of a Single System of Impedimetric Biosensors for the Detection of Mosquito-Borne Viruses. Biosensors (Basel). 2021 Oct 7;11(10):376. PMID: 34677332
CHIKV Antibodies
Ganganboina, AK. et al. (2021). Cargo encapsulated Hepatitis E virus-like particles for anti-HEV antibody detection. Biosensors and Bioelectronics. 2021 Apr.
Gaurav, N. et al. (2021). Role of nuclear localization signals in the DNA delivery function of Chikungunya virus capsid protein. Arch Biochem Biophys. 2021 Mar 15;702:108822. PMID: 33722536.
Islamuddin, M. et al. (2021). Inhibition of Chikungunya Virus Infection by 4-Hydroxy-1-Methyl-3-(3-morpholinopropanoyl)quinoline-2(1H)-one (QVIR) Targeting nsP2 and E2 Proteins. ACS Omega.
Pedraza-Escalona, M. et al. (2020). Isolation and characterization of high anity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™. Research Square (preprint).
Tuekprakhon, A. (2018). Broad-Spectrum Monoclonal Antibodies Against Chikungunya Virus Structural Proteins: Promising Candidates For Antibody-Based Rapid Diagnostic Test Development. PLOS One. PMID: 30557365
C. diff Toxin A and B
Arruda, PHE. et al. (2014). Clostridium Difficile Infection in Neonatal Piglets: Pathogenesis, Risk Factors and Prevention. Iowa State University Digital Repository.
Banz, A. et al. (2018). Sensitivity of Single-Molecule Array Assays For Detection of Clostridium Difficile Toxins In Comparison To Conventional Laboratory Testing Algorithms. Journal of Clinical Microbiology. PMID: 29898996
Banz, A. et al. (2016). Design of Two-Plex Assay For Detection of Clostridium Difficile Toxins A And B. bioMerieux.
Banz, A. et al. (2015). Development of an Ultra-Sensitive Clostridium Difficile Toxins A and B Assay Using Digital Technology. bioMerieux.
Bartolome, A. et al. (2018). Evaluation of the Singulex Clarity C. diff Toxins A/B Assay, Currently in Development of Ultrasensitive Detection of Clostridium difficile Toxins. Singulex.
Bézay, N. et al. (2016). Safety, immunogenicity and dose response of VLA84, a new vaccine candidate against Clostridium difficile, in healthy volunteers. Vaccine. May 17;34(23):2585-92. PMID: 27079932
Collery, MM. (2016). What’s a SNP Between Friends: The Influence of Single Nucleotide Polymorphisms on Virulence and Phenotypes of Clostridium Difficile Strain 630 and Derivatives. Virulence. PMID: 27652799
Cox, MA. et al. (2017). Assays for Measuring C. difficile Toxin Activity and Inhibition in Mammalian Cells. InTech Open. Chapter 5.
Dhillon, HS. et al. (2016). Homogeneous and digital proximity ligation assays for the detection of Clostridium difficile toxins A and B. Biomol Detect Quantif. Aug 31;10:2-8. PMID: 27990343
Dhillon, HS. et al. (2017). Development of Novel Molecular Methods for the Detection of C. Difficile Infections. Anglia Ruskin University.
Huang, JH. et al. (2015). Recombinant lipoprotein-based vaccine candidates against C. difficile infections. J Biomed Sci. Aug 7;22:65. PMID: 26245825
Hernandez, LD. et al. (2017). Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab. J Mol Biol. Apr 7;429(7):1030-1044. PMID: 28232034
Katzenbach, P. et al. Single Molecule Counting Technology for Ultrasensitive Quantification of Clostridium difficile Toxins A and B. Singulex.
Kelly, CP. et al. (2019). Host Immune Markers Distinguish Clostridioides Difficile Infection From Asymptomatic Carriage and Non-C. Difficile Diarrhea. Clin Infect Dis. Apr. PMID: 31211839
Kuehne, SA. et al. (2017). Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin. J Antimicrob Chemother. Dec 15. doi: 10.1093/jac/dkx486. [Epub ahead of print]. PMID: 29253242
Orth, P. et al. (2014). Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography. J Biol Chem. Jun 27;289(26):18008-21. PMID: 24821719
Rantfler, C. et al. (2021). Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff. PLoS One. 2021 May 27;16(5):e0252211. PMID: 34043688.
Sandlund, J. et al. (2018). Ultrasensitive Detection of Clostridoides difficile Toxins A and B by use of Automated Single-Molecule Counting Technology. Journal of Clinical Microbiology. PMID: 30158195
Sprague, R. et al. (2020). Absence of Toxemia in Clostridioides difficile Infection: Results from Ultrasensitive Toxin Assay of Serum. Digestive Diseases and Sciences. PMID: 33164145
Tam, S. (2018). Evaluation of an Ultrasensitive Immunoassay, Currently in Development for the Singulex Clarity System, for the Detection of Clostridium difficile Toxins A and B. Singulex.
Zhao, X. et al. (2016). Sensitive assays enable detection of serum IgG antibodies against Clostridium difficile toxin A and toxin B in healthy subjects and patients with Clostridium difficile infection. Bioanalysis. Apr;8(7):611-23. PMID: 26964649
C. diff Toxoid A and B
Anwar, S. et al. (2020). Development and verification of an enzyme-linked immunosorbent assay for the quantification of toxoid A and toxoid B from Clostridioides difficile. J Immunol Methods. 2021 Jan;488:112917. PMID: 33221460
Huang, JH. et al. (2015). Biochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A. PLoS One. Aug 13;10(8):e0135045. PMID: 26271033
Matchett, WE. et al. (2020). A Replicating Single-Cycle Adenovirus Vaccine Effective against Clostridium difficile. Vaccines. Aug 22;8(3):470. PMID: 32842679
C. diff Toxin A (Ribotype 027)
Tian, JH. et al. (2017). Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models. Vaccine. Jul 24;35(33):4079-4087. PMID: 28669616
C. diff Toxin A (Ribotype 078)
Enany, S. (2017). Clostridium Difficile: A Comprehensive Overview. Science.
Secore, S. et al. (2017). Development of a Novel Vaccine Containing Binary Toxin for the Prevention of Clostridium difficile Disease with Enhanced Efficacy against NAP1 Strains. PLoS One. Jan26;12(1):e0170640. PMID: 28125650
C. diff Toxin B Antibodies
Karyl, C. et al. (2021). Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile. Microorganisms. 2021 Feb 2;9(2):306. PMID: 33540694.
Diphtheria Toxin
Costa, DC. The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2). Cancer Lett. 2021 Oct 10;518:72-81. PMID: 34144098.
Steffie, J. Functional dissection of regulatory T cell plasticity and stability. KU Leuven (PhD thesis).
Gn protein
Golden, JW. et al. (2019). GP38-Targeting Monoclonal Antibodies Protect Adult Mice Against Lethal Crimean-Congo Hemorrhagic Fever Virus Infection. Science Advances.
Darci, RS. et al. (2019). Persistent Crimean-Congo hemorrhagic fever virus infection in the testes and within granulomas of non-human primates with latent tuberculosis. PLoS Pathogens. Sep 26;15(9). PMID: 31557262
Fels, JM. et al. (2021). Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever. Cell. May 26;S0092-8674(21)00584-5. PMID: 34077751
Nucleoprotein
Golden, JW. et al. (2019). GP38-Targeting Monoclonal Antibodies Protect Adult Mice Against Lethal Crimean-Congo Hemorrhagic Fever Virus Infection. Science Advances. PMID: 31309159.
CMV CL
Albayati, Z. et al. (2017). The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets. Scand J Immunol. Nov;86(5):396-407. PMID: 28817184
Huang, TS. et al. (2014). No evidence of association between human cytomegalovirus infection and papillary thyroid cancer. World J Surg Oncol. Feb 21;12:41. PMID: 24559116
Nabatanzi, R. et al. (2014). Low antigen-specific CD4 T-cell immune responses despite normal absolute CD4 counts after long-term antiretroviral therapy an African cohort. Immunol Lett. Dec;162(2 Pt B):264-72. PMID: 25263953
CMV Pentamer
Dorfman, JR. et al. (2021). In utero human cytomegalovirus infection is associated with increased levels of putatively protective maternal antibodies in nonprimary infection: evidence for boosting but not protection. Clin Infect Dis. 2021 Feb 9. PMID: 33560335
John, S. et al. (2018). Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity. Vaccine. 2018 Mar 14;36(12):1689-1699. PMID: 29456015
Hassett, KJ. et al. (2021). Impact of lipid nanoparticle size on mRNA vaccine immunogenicity. J Control Release. 2021 May 18;S0168-3659(21)00237-6. PMID: 34019945
Koppert, S. et al. (2021). Affinity tag coating enables reliable detection of antigen-specific B cells in ImmunoSpot assays. medRxiV (preprint).
Liu, Y. et al. (2020). A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection. J Virol. 2019 Nov 13;93(23). pii: e00747-19. PMID: 31511385
Schampera, MS. et al. (2019). Role of Pentamer Complex-Specific and IgG Subclass 3 Antibodies in HCMV Hyperimmunoglobulin and Standard Intravenous IgG Preparations. Med Microbiol Immunol. Feb, 208(1), 69-80. PMID: 30203132
CMV Lysate
Almehmadi, MM. (2014). CD56+ T-cells in Relation to Cytomegalovirus in Healthy Subjects and Kidney Transplant Patients. University of Liverpool.
Speth, P. et al. (2021). Immunocompromised Patients with Therapy-Refractory Chronic Skin Diseases Show Reactivation of Latent Epstein‒Barr Virus and Cytomegalovirus Infection. J Invest Dermatol. 2021 Sep 1;S0022-202X(21)02161-8. PMID: 34480891
CMV Antibodies
Gogesch, P. et al. (2019). Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine. Vaccines (Basel). Sep, 7(3), 104. PMID: 31480520
NS1 Proteins (All Serotypes)
Barban, V. et al. (2018). Improvement of the Dengue Virus (DENV) Nonhuman Primate Model via a Reverse Translational Approach Based on Dengue Vaccine Clinical Efficacy Data against DENV-2 and -4. Journal of Virology.
Beatty, PR. et al. (2015). Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination. Sci Transl Med. Sep 9;7(304):304ra141. PMID: 26355030
Bosch, I. et al. (2017). Rapid Antigen Tests for Dengue Virus Serotypes and Zika Virus In Patient Serum. Science Translational Medicine. PMID: 28954927
Cardenas, M and Noe, E. (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. The Open University. Mar 03. (PhD thesis).
Castanha, PMS. et al. (2019). Perinatal Analyses of Zika- and Dengue Virus-Specific Neutralizing Antibodies: A Microcephaly Case-Control Study in an Area of High Dengue Endemicity in Brazil. PLOS Neglected Tropical Diseases. PMID: 30856223
Espinosa, DA. et al. (2019). Cyclic Dinucleotide-Adjuvanted Dengue Virus Nonstructural Protein 1 Induces Protective Antibody and T Cell Responses. The Journal of Immunology. PMID: 30642979
Galula, JU. et al. (2021). Comparable Accuracies of Nonstructural Protein 1- and Envelope Protein-Based Enzyme-Linked Immunosorbent Assays in Detecting Anti-Dengue Immunoglobulin G Antibodies. Diagnostics (Basel). 2021 Apr 21;11(5):741. PMID: 33919324
Gelanew, T. et al. (2015). Development and characterization of mouse monoclonal antibodies against monomeric dengue virus non-structural glycoprotein 1 (NS1). J Virol Methods. Sep 15;222:214-23. PMID: 26070890
Glasner, DR. et al. (2017). Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components. PLoS Pathog. Nov 9;13(11):e1006673. PMID: 29121099
Goncalves, BDS. et al. (2019). Dynamics of Nonstructural glycoprotein-1 in Dengue Patients Presenting With Different Clinical Manifestations From 1986 to 2012 in Rio De Janeiro, Brazil. J Med Virol. Apr, 91(4), 555-563. PMID: 30411369
Matsunaga, K-I. et al. (2021). Competitive ELISA for a serologic test to detect dengue serotype-specic anti-NS1 IgGs using highanity UB-DNA aptamers. Research Square (preprint).
Matsunaga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Montes-Grajales, D. et al. (2020). In silico drug repurposing for the identification of potential candidate molecules against arboviruses infection. Antiviral Res. Jan;173:104668. PMID: 31786251
Nascimento, EJM. et al. (2018). Development of antibody biomarkers of long term and recent dengue virus infections. J Virol Methods. Apr 21;257:62-68. PMID: 29684416
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. Mar 19;257:48-57. PMID: 2956751
Needham, JW. et al. (2019). Interferometric Reflectance Imaging Sensor (IRIS) for Molecular Kinetics With a Low-Cost, Disposable Fluidic Cartridge. Methods Mol Biol. 2027, 15-28. PMID: 31309469
O’Donnell, K. (2020). Avian IgY As An Immunotherapy For Flaviviral Infections. University of North Dakota. Jun 12. (PhD thesis).
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Puerta-Guardo, H. et al. (2016). Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability. PLoS Pathog. Jul 14;12(7):e1005738. PMID: 27416066
Rönnberg, B. et al. (2017). Compensating for cross-reactions using avidity and computation in a suspension multiplex immunoassay for serotyping of Zika versus other flavivirus infections. Med Microbiol Immunol. Oct, 206(5):383-401. PMID: 28852878
Rogers, TF. et al. (2017). Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors. Sci Immunol. Aug 18;2(14). PMID: 28821561
Sharma, M. et al. (2019). Magnitude and Functionality of the NS1-Specific Antibody Response Elicited by a Live-Attenuated Tetravalent Dengue Vaccine Candidate. J Infect Dis. Feb 19. PMID: 30783676
Shriver-Lake, LC. et al. (2018). Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies. Scientific Reports. PMID: 30591706
Tedder, RS. et al. (2019). Modulated Zika virus NS1 conjugate offers advantages for accurate detection of Zika virus specific antibody in double antigen binding and Ig capture enzyme immunoassays, PLoS One. Aug, 14(8). PMID: 31374094
Tran, TV. et al. (2019). Development of a Highly Sensitive Magneto-Enzyme Lateral Flow Immunoassay for Dengue NS1 Detection. PeerJ. Sep, 7. PMID: 31579630
Wang, C. et al. (2019). Endocytosis of Flavivirus NS1 Is Required for NS1-mediated Endothelial Hyperpermeability and Is Abolished by a Single N-glycosylation Site Mutation. PLoS Pathog. Jul, 15(7). PMCID: PMC6687192
Warner, NL. et al. (2021). Development of Bacteriophage Virus-Like Particle Vaccines Displaying Conserved Epitopes of Dengue Virus Non-Structural Protein 1. Vaccines 2021, 9(7), 726.
Dengue Virus Serotype 1 NS1 Protein (DENV1-NS1)
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Badolato-Corrêa, J. et al. (2018). Human T cell responses to Dengue and Zika virus infection compared to Dengue/Zika coinfection. Immun Inflamm Dis. Jun;6(2):194-206. PMID: 29282904
Galula, JU. et al. (2021). Comparable Accuracies of Nonstructural Protein 1- and Envelope Protein-Based Enzyme-Linked Immunosorbent Assays in Detecting Anti-Dengue Immunoglobulin G Antibodies. Diagnostics (Basel). 2021 Apr 21;11(5):741. PMID: 33919324
Jayathilaka, D. et al. (2018). Role of NS1 Antibodies in the Pathogenesis of Acute Secondary Dengue Infection. Nature Communications. PMID: 30531923
Matsanuga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Nunes, PCG. et al. (2018). NS1 Antigenemia and Viraemia Load: Potential Markers of Progression to Dengue Fatal Outcome. Viruses. PMID: 29903980
Poltep, K. et al. (2021). Development of a Dengue Virus Serotype-Specific Non-Structural Protein 1 Capture Immunochromatography Method. Sensors 2021, 21(23), 7809.
Silva, MS. et al. (2021). Rational selection of hidden epitopes for a molecularly imprinted electrochemical sensor in the recognition of heat-denatured dengue NS1 protein. Biosensors and Bioelectronics.
Tsai, W-Y. et al. (2018). Use of Urea Wash ELISA to Distinguish Dengue Virus Infections. CDC.
Tsai, W-Y. et al. (2017). Distinguishing Secondary Dengue Virus Infection from Zika Virus Infection with Previous Dengue by a Combination of 3 Simple Serological Tools. Clinical Infectious Diseases. PMID: 29020159
Dengue Virus Serotype 2 NS1 Protein (DENV2-NS1)
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Biering, SB. et al. (2021). SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling. bioRxiv (preprint). PMID: 34931188
Chen, HR. et al. (2016). Dengue Virus Non-structural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy. PLoS Negl Trop Dis. Jul 13;10(7):e0004828. PMID: 27409803
Chen, HR. et al. (2018). Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability. PLoS Pathog. Apr 27;14(4):e1007033. PMID: 29702687
Cheung, Y. et al. (2020). A Critical Role for Perivascular Cells in Amplifying Viral Haemorrhage Induced by Dengue Virus Non-Structural Protein 1. BioRxiv. Feb 14. (Preprint).
Conde, JN. et al. (2016). Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins. J Virol. Oct 14;90(21):9570-9581. PMID: 27512066
Galula, JU. et al. (2021). Comparable Accuracies of Nonstructural Protein 1- and Envelope Protein-Based Enzyme-Linked Immunosorbent Assays in Detecting Anti-Dengue Immunoglobulin G Antibodies. Diagnostics (Basel). 2021 Apr 21;11(5):741. PMID: 33919324.
Garcia-Oliva, C. et al. (2020). Efficient Synthesis of Muramic and Glucuronic Acid Glycodendrimers as Dengue Virus Antagonists. Chemistry. Feb, 26(7), 1588-1596. PMID: 31644824
Jayathilaka, D. et al. (2018). Role of NS1 Antibodies in the Pathogenesis of Acute Secondary Dengue Infection. Nature Communications. PMID: 30531923
Lee, P. et al. (2020). Relative contribution of non-structural protein 1 in dengue pathogenesis. BioRxiv. Feb 02. (Preprint).
Mani, S. et al. (2018). Serological Cross Reactivity between Zika and Dengue Viruses in Experimentally Infected Monkeys. Virologica Sinica. PMID: 30155852
Matsanuga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Puerta-Guardo, H. et al. (2019). Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism. Cell Reports. PMID: 30726741
Tam, JO. et al. (2017). A comparison of nanoparticle-antibody conjugation strategies in sandwich immunoassays. J Immunoassay Immunochem. 38(4):355-377. PMID: 27982728
Dengue Virus Serotype 3 NS1 Protein (DENV2-NS1)
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Galula, JU. et al. (2021). Comparable Accuracies of Nonstructural Protein 1- and Envelope Protein-Based Enzyme-Linked Immunosorbent Assays in Detecting Anti-Dengue Immunoglobulin G Antibodies. Diagnostics (Basel). 2021 Apr 21;11(5):741. PMID: 33919324.
Matsanuga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Ushijima, Y. et al. (2021). Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections. BMC Infect Dis. 2021 Mar 17;21(1):265. PMID: 33731022.
Dengue Virus Serotype 4 NS1 Protein (DENV4-NS1)
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Galula, JU. et al. (2021). Comparable Accuracies of Nonstructural Protein 1- and Envelope Protein-Based Enzyme-Linked Immunosorbent Assays in Detecting Anti-Dengue Immunoglobulin G Antibodies. Diagnostics (Basel). 2021 Apr 21;11(5):741. PMID: 33919324.
Heringer, M. et al. (2017). Dengue type 4 in Rio de Janeiro, Brazil: case characterization following its introduction in an endemic region. BMC Infect Dis. Jun 9;17(1):410. PMID: 28599640
Matsanuga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Ushijima, Y. et al. (2021). Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections. BMC Infect Dis. 2021 Mar 17;21(1):265. PMID: 33731022.
Dengue Virus Serotype 2 Lysate
Nagar, PK. et al. (2020). Detection of Dengue Virus-Specific IgM and IgG Antibodies through Peptide Sequences of Envelope and NS1 Proteins for Serological Identification. Journal of Immunology Research. 2020 August 4th: 1-8.
Dengue Envelope Proteins
Durham, N. et al. (2019). Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics. BioRxiv. Oct 02. (Preprint).
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Rogers, TF. et al. (2017). Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors. Sci Immunol. Aug 18;2(14). PMID: 28821561
Dengue Virus-Like Particles
Awadalkareem, A. et al. (2018). Multiplexed FluroSpot for the Analysis of Dengue Virus- and Zika Virus-Specific and Cross-Reactive Memory B Cells. The Journal of Immunology. PMID: 30413671
Deliot, A. et al. (2017) Visualization of Dengue virus like particles interacting with antibodies. The 16th European Microscopy Congress, Lyon, France.
Goldman, ER. et al. (2017). Bglbrick strategy for the construction of single domain antibody fusions. Heliyon. Dec 28;3(12):e00474. PMID: 29322100
Lecouturier, V. et al. (2018). Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclonal antibodies targeting key conformational epitopes. Vaccine. Apr 26. pii: S0264-410X(18)30562-0. PMID: 29706291
Metz, SW. et al. (2018). Dengue virus-like particles mimic the antigenic properties of the infectious dengue virus envelope. Virol J. 2018 Apr 2;15(1):60. PMID: 29609659
Nascimento, EJ. et al. (2021). Development and Characterization of a Multiplex Assay to Quantify Complement-Fixing Antibodies against Dengue Virus. Int J Mol Sci. 2021 Nov 5;22(21):12004. PMID: 34769432
Ponndorf, D. et al. (2020). Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice. Plant Biotechnology Journal. PMID: 33099859
Sanchez-Vargas, LA. et al. (2019). Longitudinal Analysis of Memory B and T Cell Responses to Dengue Virus in a 5-Year Prospective Cohort Study in Thailand. Front Immunol. Jun, 10, 1359. PMID: 31263466
Seiler, BT. (2019). Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000 Research. PMID: 31275563.
Tsuji, I. et al. (2021). Development of a novel assay to assess the avidity of dengue virus-specific antibodies elicited in response to a tetravalent dengue vaccine. J Infect Dis. 2021 Feb 3;jiab064. PMID: 33534885.
Dengue Virus Antibodies
Pedraza-Escalon, M. et al. (2020). Isolation and characterization of high anity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™. Research Square (preprint).
Ponndorf, D. et al. (2020). Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice. Plant Biotechnology Journal. PMID: 33099859
Tuekprakhon, A. et al. (2018). Broad-spectrum monoclonal antibodies against chikungunya virus structural proteins: Promising candidates for antibody-based rapid diagnostic test development. PLoS One. PMID: 30557365
Warner, NL. et al. (2021). Development of Bacteriophage Virus-Like Particle Vaccines Displaying Conserved Epitopes of Dengue Virus Non-Structural Protein 1. Vaccines 2021, 9(7), 726.
GP1
Seiler, BT. (2019). Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000 Research. PMID: 31275563.
HBV Envelope
Abdulkarem, AA. (2021). Understanding the viral diversity of Hepatitis B virus in Saudi Arabia using Next Generation Sequencing (NGS). PhD thesis, University of Glasgow.
HSV-2 Antibodies
Horton, MS. et al. (2021). Development of a microneutralization assay for HSV-2. J Virol Methods. 2021 Aug 24;297:114268. PMID: 34437874.
Misc.
Mahari, S. et al. (2020). eCovSens-Ultrasensitive Novel In-House Built Printed Circuit Board Based Electrochemical Device for Rapid Detection of nCovid-19 antigen, a spike protein domain 1 of SARS-CoV-2. BioRxiv. Apr 29. (Preprint).
Haemagglutinin
Iriarte-Alonso, MA. et al. (2021). Influenza A virus hemagglutinin prevents extensive membrane damage upon dehydration. BioRxiV (preprint).
Rosado, J. et al. (2021). Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study. Lancet Microbe. 2021 Feb;2(2):e60-e69. PMID: 33521709.
Yang, F. et al. (2021). Phage Display-Derived Peptide for the Specific Binding of SARS-CoV-2. ACS Publications. 2021 Dec.
Neuraminidase
Vatzia, E. et al. (2021). Respiratory and intramuscular immunization with ChAdOx2 NPM1-NA induces distinct immune responses in H1N1pdm09 pre-exposed pigs. Research Square (preprint).
Misc.
Mahari, S. et al. (2020). eCovSens-Ultrasensitive Novel In-House Built Printed Circuit Board Based Electrochemical Device for Rapid Detection of nCovid-19 antigen, a spike protein domain 1 of SARS-CoV-2. BioRxiv. Apr 29. (Preprint).
JEV NS1
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Mahari, S. et al. (2020). eCovSens-Ultrasensitive Novel In-House Built Printed Circuit Board Based Electrochemical Device for Rapid Detection of nCovid-19 antigen, a spike protein domain 1 of SARS-CoV-2. BioRxiv. Apr 29. (Preprint).
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018 Mar 19;257:48-57. PMID: 2956751
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Puerta-Guardo, H. et al. (2019). Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism. Cell Reports. PMID: 30726741
Roberts, A. et al. (2020). Graphene functionalized field-effect transistors for ultrasensitive detection of Japanese encephalitis and Avian influenza virus. Sci Rep. Sep 3;10(1). PMID: 32884083
Shriver-Lake, LC. et al. (2018). Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies. Scientific Reports. PMID: 30591706
JEV Antibodies
Pedraza-Escalon, M. et al. (2020). Isolation and characterization of high anity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™. Research Square (preprint).
Roberts, A. et al. (2020). Graphene functionalized field-effect transistors for ultrasensitive detection of Japanese encephalitis and Avian influenza virus. Sci Rep. Sep 3;10(1). PMID: 32884083
Tuekprakhon, A. et al. (2018). Broad-spectrum monoclonal antibodies against chikungunya virus structural proteins: Promising candidates for antibody-based rapid diagnostic test development. PLoS One. PMID: 30557365
LASV GP1 and GP2
Akpogheneta, O. et al. (2021). Boosting understanding of Lassa Fever virus epidemiology: Field testing a novel assay to identify past Lassa Fever virus infection in blood and oral fluids of survivors and unexposed controls in Sierra Leone. PLoS Neg. Tr. Dis.
Muller, EM. et al. (2020). Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity. NPJ Vaccines, 70: 1-17.
LASV Nucleoprotein
Kennedy, EM. et al. (2019). A Vaccine Based on Recombinant Modified Vaccinia Ankara Containing the Nucleoprotein From Lassa Virus Protects Against Disease Progression in a Guinea Pig Model. Vaccine, 37(36), 5404-5413. PMID: 31331770
Antibodies
Akpogheneta, O. et al. (2021). Boosting understanding of Lassa Fever virus epidemiology: Field testing a novel assay to identify past Lassa Fever virus infection in blood and oral fluids of survivors and unexposed controls in Sierra Leone. PLoS Neg. Tr. Dis.
Measles Virus
Measles Virus Immunoassays
Veklych, K. et al. (2021). Features of toll-like receptor type 9 expression on immunocompetent peripheral blood cells of patients with measles infection of varying severity. ScienceRise.
Nipah Virus
Glycoprotein
Doremalen, NV. et al. (2021). ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys. BioRxiv (preprint).
Nucleoprotein
Doremalen, NV. et al. (2021). ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys. BioRxiv (preprint).
NoV GII.4 VLP
Gorji, ME. et al (2021). Influence of fucosidase-producing bifidobacteria on the HBGA antigenicity of oyster digestive tissue and the associated norovirus binding. Int J Food Microbiol. 2021 Feb 16;340:109058. PMID: 33461001
Malcom, THT. et al (2021). Fucoidan But Not 2′-Fucosyllactose Inhibits Human Norovirus Replication in Zebrafish Larvae. Viruses 2021, 13(3), 461.
Mirabelli, C. et al. (2021). Human norovirus infection of primary B cells triggers immune activation in vitro. BioRxiv (preprint).
NoV GII. Antibodies
Malcom, THT. et al (2021). Fucoidan But Not 2′-Fucosyllactose Inhibits Human Norovirus Replication in Zebrafish Larvae. Viruses 2021, 13(3), 461.
Rubella VLPs
Rosado, J. et al. (2021). Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study. Lancet Microbe. 2021 Feb;2(2):e60-e69. PMID: 33521709.
Lysate
Soulier, A. et al. (2021). Engineering a Novel Bivalent Oral Vaccine against Enteric Fever. Int J Mol Sci. 2021 Mar; 22(6): 3287. PMCID: PMC8005139.
Sheep HRP Antibody
Gogesch, P. et al. (2019). Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine. Vaccines (Basel). Sep, 7(3), 104. PMID: 31480520
Rabbit Anti-Sheep IgG (H + L)
Shaw, AM. et al. (2020). Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome. Analyst. 2020 July 07: 5638-5646.
Streptococcus
Native Antigen
Karakus, E. et al. (2021). Colorimetric and electrochemical detection of SARS-CoV-2 spike antigen with a gold nanoparticle-based biosensor. Analytica Chimica Acta. 2021 Oct 16; 1182: 338939.
Lokman, Liv. (2021). A rapid, ultrasensitive voltammetric biosensor for determining SARS-CoV-2 spike protein in real samples. Biosens Bioelectron. 2021 Nov 15; 192: 113497. PMCID: PMC8276568.
TBEV NS1
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Albinsson, B. (2018). Distinction Between Serological Responses Following Tick-Borne Encephalitis Virus (TBEV) Infection Vs Vaccination, Sweden 2017. Eurosurveillance. PMID: 29386094
Cardenas, M and Noe, E. (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. The Open University. Mar 03. (PhD thesis).
Girl, P. (2020). Frühsommer-Meningoenzephalitis-Virus ─Der Nutzen von Antikörpern gegen das Nicht-Strukturprotein 1 (NS1) in der Diagnostik. (PhD thesis).
Girl, P. et al. (2020). Tick-borne Encephalitis Virus (TBEV): Non-Structural Protein (NS1) IgG ELISA Differentiating Infection vs. Vaccination Antibody Responses. J Clin Microbiol. Jan. PMID: 31969423
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. Mar 19;257:48-57. PMID: 2956751
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Salat, J. et al. (2020). Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals. Vaccines (Basel). Feb 12;8(1). pii: E81. PMID: 32059489
Seiler, BT. (2019). Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000 Research. PMID: 31275563
Shriver-Lake, LC. et al. (2018). Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies. Scientific Reports. PMID: 30591706
Tagliabue, G. et al. (2017). A label-free immunoassay for Flavivirus detection by the Reflective Phantom Interface technology. Biochem Biophys Res Commun. Oct 28;492(4):558-564. PMID: 28501619
Trichomonas vaginalis antigen
Seiler, BT. (2019). Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000 Research. PMID: 31275563
Usutu Virus NS1 Protein
Cardenas, M and Noe, E. (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. The Open University. Mar 03. (PhD thesis).
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018 Mar 19;257:48-57. PMID: 2956751
Saiz, J-C. and Blazquez, A-B. (2017). Usutu Virus: Current Knowledge and Future Perspectives. Virus Adaptation and Treatment.
WNV NS1 Protein
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Beatty, PR. et al. (2015). Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination. Sci Transl Med. Sep 9;7(304):304ra141. PMID: 26355030
Cardenas, M and Noe, E. (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. The Open University. Mar 03. (PhD thesis).
Conde, JN. et al. (2016). Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins. J Virol. Oct 14;90(21):9570-9581. PMID: 27512066
Glasner, DR. et al. (2017). Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components. PLoS Pathog. Nov 9;13(11):e1006673. PMID: 29121099
Gelanew, T. et al. (2015). Development and characterization of mouse monoclonal antibodies against monomeric dengue virus non-structural glycoprotein 1 (NS1). J Virol Methods. Sep 15;222:214-23. PMID: 26070890
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018 Mar 19;257:48-57. PMID: 2956751
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Puerta-Guardo, H. et al. (2016). Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability. PLoS Pathog. Jul 14;12(7):e1005738. PMID: 27416066
Puerta-Guardo, H. et al. (2019). Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism. Cell Reports. PMID: 30726741
Shriver-Lake, LC. et al. (2018). Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies. Scientific Reports. PMID: 30591706
Tagliabue, G. et al. (2017). A label-free immunoassay for Flavivirus detection by the Reflective Phantom Interface technology. Biochem Biophys Res Commun. Oct 28;492(4):558-564. PMID: 28501619
WNV Antibodies
Pedraza-Escalon, M. et al. (2020). Isolation and characterization of high anity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™. Research Square (preprint).
Tuekprakhon, A. et al. (2018). Broad-spectrum monoclonal antibodies against chikungunya virus structural proteins: Promising candidates for antibody-based rapid diagnostic test development. PLoS One. PMID: 30557365
YFV NS1 Protein
Abraham, PR. et al. (2021). Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes. Sci Rep. 2021 Dec 8;11(1):23699. PMID: 34880307
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018 Mar 19;257:48-57. PMID: 2956751
Gelanew, T. et al. (2015). Development and characterization of mouse monoclonal antibodies against monomeric dengue virus non-structural glycoprotein 1 (NS1). J Virol Methods. Sep 15;222:214-23. PMID: 26070890
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Puerta-Guardo, H. et al. (2019). Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism. Cell Reports. PMID: 30726741
Shriver-Lake, LC. et al. (2018). Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies. Scientific Reports. PMID: 30591706
Yen, CW. et al. (2015). Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses. Lab Chip.7;15(7):1638-41. PMID: 25672590
ZIKV Envelope Protein
Fowler, AM. et al. (2018). Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice. Cell Host & Microbe. PMID: 30439343
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Ponndorf, D. et al. (2020). Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice. Plant Biotechnology Journal. PMID: 33099859
Salazar, V. et al. (2019). Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect Against Spondweni Virus Infection and Pathogenesis in Mice. Cell Reports. PMID: 30726740
Valenzuela-Leon, PC. et al. (2022). Multiple Salivary Proteins from Aedes aegypti Mosquito Bind to the Zika Virus Envelope Protein. Viruses 2022, 14(2), 221.
Wen, J. et al. (2017). Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge. Nat Commun. Nov 13;8(1):1459. PMID: 29129917
T.Langerak (2022) Transplacental Zika virus transmission in ex vivo perfused human placentas https://doi.org/10.1371/journal.pntd.0010359
ZIKV NS1 Protein
Afsahi, S. et al. (2018). Novel graphene-based biosensor for early detection of Zika virus infection. Biosens Bioelectron. 100:85-88. PMID: 28865242
Balmaseda, A. et al. (2017). Antibody-based assay discriminates Zika virus infection from other flaviviruses. Proc Natl Acad Sci U S A. Aug 1;114(31):8384-8389. PMID: 28716913
Balmaseda, A. et al. (2018). Comparison of four serological methods and two RT-PCR assays for diagnosis and surveillance of Zika. J Clin Microbiol. Jan 5. pii: JCM.01785-17. doi: 10.1128/JCM.01785-17. [Epub ahead of print]. PMID: 29305550
Bedin, F. et al. (2017). Paper-based point-of-care testing for cost-effective diagnosis of acute flavivirus infections. J Med Virol. Sep;89(9):1520-1527. PMID: 28295400
Bhardwaj, U. and Singh, SK. (2021). Zika Virus NS1 Suppresses VE-Cadherin and Claudin-5 via hsa-miR-101-3p in Human Brain Microvascular Endothelial Cells. Mol Neurobiol. 2021 Sep 6. PMID: 34487317.
Bosch, I. et al. (2017). Rapid Antigen Tests for Dengue Virus Serotypes and Zika Virus In Patient Serum. Science Translational Medicine. PMID: 28954927
Cardenas, M and Noe, E. (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. The Open University. Mar 03. (PhD thesis).
Chao, C-H. et al. (2019). Dengue Virus Nonstructural Protein 1 Activate Platelets via Toll-Like Receptor 4, Leading to Thrombocytopenia and Hemorrhage. PLOS Pathogens. PMID: 31009511
Conde, JN. et al. (2016). Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins. J Virol. Oct 14;90(21):9570-9581. PMID: 27512066
Ganganboina, AB. et al. (2021). Cargo encapsulated hepatitis E virus-like particles for anti-HEV antibody detection. Biosens Bioelectron. 2021 Aug 1;185:113261. PMID: 33962156
Henry, P-G. et al. (2020). Zika Virus Nonstructural Protein 1 Disrupts Glycosaminoglycans and Causes Permeability in Developing Human Placentas. J Infect Dis. Jan, 221(2), 313-324. PMID: 31250000
Kareinen, L. et al. (2019). Immunoassay for serodiagnosis of Zika virus infection based on time-resolved Förster resonance energy transfer. PLoS One. Jul, 14(7). PMID: 31335898
Katzelnick, LC. et al. Zika virus infection enhances future risk of severe dengue disease. Science. Aug, 369(6507):1123-1128. PMID: 32855339
Lecouturier, V. et al. (2019). Immunogenicity and Protection Conferred by an Optimized Purified Inactivated Zika Vaccine in Mice. Vaccine. May, 37(2), 2679-2686. PMID: 30967310
Lecouturier, V. et al. (2020). An optimized purified inactivated Zika vaccine provides sustained immunogenicity and protection in cynomolgus macaques. NPJ Vaccines. Mar 12;5:19. PMID: 32194996
Limonta, D. et al. (2018). Human Fetal Astrocytes Infected with Zika Virus Exhibit Delayed Apoptosis and Resistance Interferon: Implications for Persistance. Viruses. PMID: 30453621
Margulis, M. et al. (2021). Optical modulation biosensing system for rapid detection of biological targets at low concentrations. Biomedical Optics Express. Vol. 12, Issue 9, pp. 5338-5350 (2021).
Matsanuga, K-I. et al. (2021). High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification. Nucleic Acids Res. 2021 Jun 25;gkab515. PMID: 34169309
Merbah, M. et al. (2020). A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins. J Immunol Methods. 2020 Oct 3;112874. PMID: 33022219.
Michelson, Y. et al. (2019). Highly Sensitive and Specific Zika Virus Serological Assays Using a Magnetic Modulation Biosensing System. J Infect Dis. Mar, 219(7), 1035-1043. PMID: 30335151
Nascimento, EJM. et al. (2018). Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. Mar 19;257:48-57. PMID: 2956751
Nascimento, EJM. et al. (2019). Use of a Blockade-of-Binding ELISA and Microneutralization Assay to Evaluate Zika Virus Serostatus in Dengue-Endemic Areas. Am J Trop Med Hyd. Sep 101(3);708-715. PMC6726926
Park, C. et al. (2020). A Simple Method for the Design and Development of Flavivirus NS1 Recombinant Proteins Using an In Silico Approach. Biomed Res Int. Feb 13;2020:3865707. PMID: 32104691
Puerta-Guardo, H. et al. (2019). Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism. Cell Reports. PMID: 30726741
Puerta-Guardo, et al. (2020). Zika Virus Nonstructural Protein 1 Disrupts Glycosaminoglycans and Causes Permeability in Developing Human Placentas. J Infect Dis. Jan 2;221(2):313-324. PMID: 31250000
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ZIKV Lysate
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ZIKV VLPs
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ZIKV Antibodies
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ZIKV ELISA
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