0 Items
Select Page

Listeria

Listeria monocytogenes is the causative agent of a rare but severe and life threatening food-borne disease known as listeriosis. In most people, Listeria monocytogenes infection may cause a self-limiting febrile illness. In pregnant women, newborn babies and immunocompromised people, the disease can cause severe illness or even death. Although the number of annual reported cases of Listeriosis are relatively small, the high risk of mortality in these individuals is of significant global health concern.

To support Listeria monocytogenes research, we have developed antibodies that work together as a matched pair in ELISA assays, and are suitable for immunoassay research and development.

Listeria Background

Listeria monocytogenes is the causative agent of a severe and life-threatening food-borne disease known as listeriosis.

In nature, L. monocytogenes (Lm) is ubiquitous in soil, water, animal waste and decaying plants, where it acts as a saprophyte. Transmission of Lm to humans can occur via a diverse range of food types including pre-cooked contaminated meat, unpasteurised dairy products, soft cheese, vegetables, fruit and undercooked ready-to-eat food products.

In healthy adults, Lm infection may be asymptomatic or cause a self -limiting flu-like illness with vomiting and diarrhoea. However, in the elderly, newborn infants and immunocompromised individuals, invasive L.monocytogenes infection can occur leading to life-threatening diseases such as meningitis and septicaemia. In pregnant women, infection of the foetus in utero can cause spontaneous abortion (CDC).

Although the number of annual reported cases of Listeriosis are relatively small, most patients with listeriosis require hospitalisation and the risk of death is high in these cases. In addition, Lm infection is the reported to be the third leading cause of foodborne death and is therefore a global health concern.

References

Centers for Disease Control and Prevention: Listeria (Listeriosis)

Listeria Antibodies

The Native Antigen Company supply monoclonal antibodies designed for Listeria monocytogenes immunoassay research and development. Our monoclonal antibodies MAB12259 (clone LZF7) and MAB12260 (clone LZH1) work together as a capture- detection antibody pair in sandwich immunoassays.

Questions?

Check out our FAQ section for answers to the most frequently asked questions about our website and company.

A Q&A with David Flavell of Leukaemia Busters

In this blog, we speak with Dr. David Flavell about his scientific career, the legacy of Leukaemia Busters, and the recent impact that COVID-19 has had on his research.Tell me about your scientific background David. I was born in a seaside town called Southport in...

Avoiding the Immunopathology Pitfalls of a COVID-19 Vaccine

In the second of a three-part series on COVID-19 vaccines, we explore the potential challenges in stimulating safe vaccine responses and outline the role that diagnostics will play in guiding their development.Rogue Responses Antibodies play a crucial role in...

The Bumpy Road to a Cytomegalovirus Vaccine

The development of a cytomegalovirus vaccine has been 50 years in the making. Are there any technologies in the pipeline that could prompt a breakthrough? This article was originally posted online at The Medicine Maker, a Texere publication.To say that...

Why We Need Antigen and Antibody Tests for COVID-19

RT-PCR is the workhorse of viral diagnosis and has been invaluable in COVID-19 case confirmation and isolation guidance. However, while fast and sensitive, PCR suffers from some inherent drawbacks that limit it to diagnosis during the acute phase of infection. To...

Gonorrhea: What’s Currently in the Clinical Pipeline?

This article was written by our friends at Infectious Diseases Hub, a free-to-access website that aims to deliver up-to-date, essential research and information on all aspects of microbiology, virology, mycology and parasitology – from bench to bedside....

Get in Touch

We sometimes send exclusive information and offers to our customers - please let us know if you are happy to receive these

4 + 10 =

Live Customer Feedback

Join our mailing list

* indicates required