0 Items
Select Page

Listeria

Listeria monocytogenes is the causative agent of a rare but severe and life threatening food-borne disease known as listeriosis. In most people, Listeria monocytogenes infection may cause a self-limiting febrile illness. In pregnant women, newborn babies and immunocompromised people, the disease can cause severe illness or even death. Although the number of annual reported cases of Listeriosis are relatively small, the high risk of mortality in these individuals is of significant global health concern.

To support Listeria monocytogenes research, we have developed antibodies that work together as a matched pair in ELISA assays, and are suitable for immunoassay research and development.

Listeria Background

Listeria monocytogenes is the causative agent of a severe and life-threatening food-borne disease known as listeriosis.

In nature, L. monocytogenes (Lm) is ubiquitous in soil, water, animal waste and decaying plants, where it acts as a saprophyte. Transmission of Lm to humans can occur via a diverse range of food types including pre-cooked contaminated meat, unpasteurised dairy products, soft cheese, vegetables, fruit and undercooked ready-to-eat food products.

In healthy adults, Lm infection may be asymptomatic or cause a self -limiting flu-like illness with vomiting and diarrhoea. However, in the elderly, newborn infants and immunocompromised individuals, invasive L.monocytogenes infection can occur leading to life-threatening diseases such as meningitis and septicaemia. In pregnant women, infection of the foetus in utero can cause spontaneous abortion (CDC).

Although the number of annual reported cases of Listeriosis are relatively small, most patients with listeriosis require hospitalisation and the risk of death is high in these cases. In addition, Lm infection is the reported to be the third leading cause of foodborne death and is therefore a global health concern.

References

Centers for Disease Control and Prevention: Listeria (Listeriosis)

Listeria Antibodies

The Native Antigen Company supply monoclonal antibodies designed for Listeria monocytogenes immunoassay research and development. Our monoclonal antibodies MAB12259 (clone LZF7) and MAB12260 (clone LZH1) work together as a capture- detection antibody pair in sandwich immunoassays.

Questions?

Check out our FAQ section for answers to the most frequently asked questions about our website and company.

Why We Need Antigen and Antibody Tests for COVID-19

RT-PCR is the workhorse of viral diagnosis and has been invaluable in COVID-19 case confirmation and isolation guidance. However, while fast and sensitive, PCR suffers from some inherent drawbacks that limit it to diagnosis during the acute phase of infection. To...

Gonorrhea: What’s Currently in the Clinical Pipeline?

This article was written by our friends at Infectious Diseases Hub, a free-to-access website that aims to deliver up-to-date, essential research and information on all aspects of microbiology, virology, mycology and parasitology – from bench to bedside....

Novel Coronavirus Antigens Now Available

The Native Antigen Company is now offering recombinant S1 and S2 glycoproteins for SARS-CoV-2 (Covid-19) in response to urgent demand. These reagents are suitable for use in basic research and the development of diagnostics and vaccines.These antigens have been...

The Why and How of Protein Conjugation

In this blog, Lead Assay Development Scientist, Toni Ertl discusses the basics of protein conjugation and introduces our new range of conjugation kits for the labelling of antigens and antibodies.Detecting Proteins If you’re trying to detect or measure the presence...

Going Viral: Why We Need New Diagnostics For a Safe and Effective Dengue Vaccine

This article is taken from European Biopharmaceutical Review January 2020, pages 44-46. © Samedan Ltd.The Dengue VirusDengue is the world’s most prevalent and consequential arboviral disease. Current estimates indicate that as many as 390 million dengue infections...

Get in Touch

We sometimes send exclusive information and offers to our customers - please let us know if you are happy to receive these

4 + 15 =

Live Customer Feedback

Join our mailing list

* indicates required