USUTU VIRUS NS1 PROTEIN

Usutu virus NS1 protein 1 (Non-Structural 1) has been manufactured in response to the unmet need for highly purified, concentrated protein for use in serological based diagnostic assays. Usutu virus NS1 protein is engineered in human cells using state-of-the-art expression and purification techniques.

PRODUCT DETAILS – USUTU VIRUS NS1 PROTEIN

• Recombinant Usutu virus NS1 protein (strain Vienna 2001, NCBI Accession Number: AWC68492.1) produced from HEK293 cells.
• Includes amino acids 794-1145 and a C-terminal His-tag.
• Greater than 95% purity by SDS-PAGE and buffered in DPBS pH 7.4.

BACKGROUND

Usutu virus is an emerging disease that is spread by Culex mosquitoes to wild birds (Blackbird pictured above) or bats which act as amplifying hosts, and to humans which act as accidental or dead-end hosts. The virus was first described in 1959 in South Africa, and has spread to Europe in or before 1996. In 2009 the first case of neuroinvasive Usutu virus infection was described in a 60-year old woman in Italy. More neuroinvasive infections caused by Usutu virus were described in a Croatian study in 2013. There is no vaccine or specific treatment available for Usutu virus.

Usutu virus NS1 protein has been produced to the same standards as other NS1 proteins, and is presented as a highly purified liquid protein.

****SHIPPING NOTIFICATION: All NS1 products are shipped at ambient temperature. Extensive stability tests have shown no negative effects on antigen performance for 7 days of shipping. Should customers desire shipment on dry ice, this can be performed for an extra fee, please get in contact with us by phone or email.****