GOAT ANTI-STAPHYLOCOCCUS AUREUS ANTIBODY

Goat anti-Staphylococcus aureus antibody is an affinity purified antibody isolated from a pool of serum from goats immunized with Staphylococcus aureus.

PRODUCT DETAILS – GOAT ANTI-STAPHYLOCOCCUS AUREUS ANTIBODY

• Part of the BacTrace® range of antigens and antibodies.
• Affinity purified antibody made in goat.
• Isolated from a pool of serum from goats immunized with Staphylococcus aureus.
• This product is designed to react specifically with Staphylococcus aureus. Minimal cross-reactivity may exist to other similar species.
• Product is in lyophilized form.
• Each lot is tested to assure specificity and lot-to-lot consistency using an in-house ELISA assay.

BACKGROUND

Staphylococcus aureus is a Gram-positive, round-shaped bacterium, a member of the Firmicutes, and in humans is frequently found in the upper respiratory tract and on the skin. S. aureus can also survive on dogs, cats, and horses, and can cause bumblefoot in chickens. The nasal region has been implicated as the most important site of transfer between dogs and humans. S. aureus is one of the causal agents of mastitis in dairy cows. Although S. aureus usually acts as a commensal of the human microbiota it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing virulence factors such as potent protein toxins, and the expression of a cell-surface protein that binds and inactivates antibodies. The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem in clinical medicine. S. aureus is also responsible for food poisoning. Depending on the strain, S. aureus is capable of secreting several exotoxins (Oliveira et al., 2018). Many of these toxins are associated with specific diseases and it is capable of generating toxins that produce food poisoning in the human body. Its incubation period lasts one to six hours, with the illness itself lasting from 30 minutes to 3 days. Despite much research and development, no vaccine for S. aureus has been approved. Up to 50,000 deaths each year in the USA are linked with S. aureus infections.

REFERENCES

• Oliveira D, Borges A, Simões M. Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases. Toxins (Basel). 2018 Jun 19;10(6):252.