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Mouse IgG2a Isotype Control Antibody:Biotin (HOPC-1)

$237.15 excl. VAT

Mouse monoclonal antibody IgG2a isotype control, conjugated to Biotin.

SKU: MAB12223 Categories: ,

MOUSE IGG2A ISOTYPE CONTROL ANTIBODY:BIOTIN (HOPC-1)

Mouse IgG2a isotype control antibody is supplied as a purified monoclonal antibody conjugated to biotin. The antibody is suitable for use as a negative control in a wide range of applications.

 

PRODUCT DETAILS – MOUSE IGG2A ISOTYPE CONTROL ANTIBODY:BIOTIN (HOPC-1)

  • Mouse monoclonal IgG2a antibody (clone HOPC-1), suitable for use as a negative control.
  • Greater than 95% purity by SDS-PAGE and buffered in PBS pH7.4.

 

BACKGROUND

Isotype controls are a type of negative control designed to measure the level of non-specific background signal caused by primary antibodies. The background signal is often the result of immunoglobulins binding non-specifically to Fc receptors present on the cell surface. For example, antibodies raised in mice may bind to some human cells regardless of the test antibody specificity, in a manner related to the isotype of the antibody being used. In these cases you need an isotype control of the same isotype as the test antibody to provide a relevant control for non-specific binding.

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