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Protein Purification

Purification of recombinant or native proteins can be a demanding task, which we achieve using the experience of our protein scientists and their battery of purification options.

Purifying your protein

Our steps for purifying your protein will begin with a discussion with you about your requirements, which may not simply be for a certain degree of purity, but can include functional activity, removal of specific contaminants and bespoke buffer requirements. Following that consultation we will develop a strategy for the purification, which may include several steps.

Our column chromatography suite includes state of the art AKTA equipment, and a full range of chromatography techniques including affinity chromatography, ion exchange chromatography, size exclusion chromatography and hydrophobic interaction chromatography. These techniques are supported by a full range of analytical techniques, including SDS-PAGE, Western Blot and ELISA.

“The purity of my custom expressed proteins, developed using a number of different tagging systems, has always been excellent.”

– Peter Laing, CEO, Excivion Ltd

“Thank you so much for all the useful information! Believe it or not it’s actually very refreshing to talk to someone who really knows about the science behind the products, and who is able to give genuine advice on reagents best suited to a given study. I really appreciate your help on this, so really no need to apologise for going into so much detail! I think the CMV-HP reagent would be perfect for us to start with.

– Anya

“Both the service received and the quality of​ products are excellent. Thanks so much for your help with the quote and purchase. Will contact you in the future.”

– Wei-Kung

Zika - development of mature VLPs

Preparation of mature Zika Virus-like particles for EM analysis, developed from our catalogue product for a specific customer requirement

Mutated Dengue Envelope proteins

Development of site-directed mutants of Dengue virus envelope proteins in support of vaccine R&D

Expression and purification of intracellular protein

Preparation of highly purified, bioactive protein, to support oncology clinical trials

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