Lambda Variant Spike Antigens Now Available

To support the research, development and validation of diagnostics and vaccines, The Native Antigen Company now offers trimeric whole Spike and RBD antigens for the SARS-CoV-2 Lambda (C37) variant.

Lambda Spike Products

The Native Antigen Company now offers two Spike antigens for the SARS-CoV-2 Delta variant:

Our trimeric whole Spike antigen is stabilised as a pre-fusion trimer via six amino acid (HexaPro) changes in the S2 subunit, in addition to a GSAS mutation in the furin cleavage site and a His-2xStrep-tag at the C-terminus for ease of purification.

Our Spike receptor-binding domain (RBD) antigen includes residues 319-542 of the full Spike sequence and a C-terminal His-tag for ease of purification.

These antigens are available in 100μg and 500μg sizes, as well as bulk supply of multiple grams.

Antigen	Mutations in Reference to Wuhan-Hu-1 Wild-Type
Whole Spike (REC31976)	G75V T76I 246-252del D253N L452Q F490S D614G Q675H T859N
Spike RBD (REC31992)	L452Q F490S

Produced with our VirtuE™ expression system, our Spike antigens exhibit full glycosylation and proper folding, ideal for developing high quality immunoassays and raising highly specific antibodies.

For more information on these products, click the buttons below or get in touch with a member of our team:

Whole Spike (REC31976)

Spike RBD (REC31992)

Our SARS-CoV-2 Reagents

We’re continuing to develop a range of Spike protein mutants for emerging variants, as well as offering a broad panel of variant-specific antibodies and neutralisation development kits.

For more information on these products, click the buttons below:

See Our Mutant Pipeline

See our Variant-Specific Antibodies

See our Neutralisation Development Kits

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