Search results: “ACE2”
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Human ACE2 (18-615) Recombinant Protein, Sheep Fc-Tag (HEK293)
Recombinant human angiotensin-converting enzyme 2 (ACE2) extracellular domain (18-615) was expressed in HEK293 cells using a C-terminal sheep Fc-tag and purified to SARS-CoV-2 receptor binding domain (RBD) of the spike protein binds to the host cell ACE2 receptor to facilitate viral entry into the cell. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (Lambda Variant RBD-ACE2)
LAMBDA VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (Lambda variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (Omicron Variant SPIKE-ACE2)
OMICRON VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (Omicron variant SPIKE-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (Delta Variant RBD-ACE2)
DELTA VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (Delta variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (Kerala Variant RBD-ACE2)
KERALA (KAPPA/B.1.617.1) VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (Kerala variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (Brazilian Variant RBD-ACE2)
BRAZILIAN VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (BZ variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (South African Variant RBD-ACE2)
SOUTH AFRICAN VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (SA variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (United Kingdom Variant RBD-ACE2)
UNITED KINGDOM (UK) VARIANT This SARS-CoV-2 Neutralization Assay Development Kit (UK variant RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Neutralization Assay Development Kit (RBD-ACE2)
Wild-Type (Wuhan-Hu-1) This SARS-CoV-2 Neutralization Assay Development Kit (RBD-ACE2) is intended for the identification and qualitative measurement of neutralizing antibodies. Kit contains enough reagents for 10 x 96-well plates. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Rabbit IgG Anti-SARS-CoV-2 Spike (S1) Antibody (CR3022)
Rabbit IgG anti SARS-CoV-2 Spike (S1) is a monoclonal antibody that recognizes the the SARS-CoV and SARS-CoV-2 Spike glycoprotein, the causative agent of COVID-19. Antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity at amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the Spike protein.
Human IgM Anti-SARS-CoV-2 Spike (S1) Antibody (CR3022)
Human IgM anti SARS-CoV-2 Spike antibody (CR3022) is a recombinant monoclonal antibody that recognizes the SARS-CoV and SARS-CoV-2 Spike glycoprotein, the causative agent of COVID-19. The antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity at amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the Spike protein.
Human IgG1 Anti-SARS-CoV-2 Spike (S1) Antibody (CR3022)
Human IgG1 anti SARS-CoV-2 Spike (S1) antibody (CR3022) is a monoclonal antibody that recognizes the SARS-CoV and SARS-CoV-2 Spike glycoprotein, the causative agent of COVID-19. Antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity at amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the Spike protein. Antibody recognizes RBD from Wuhan-Hu-1, UK (Alpha), South African (Beta) Brazilian (Gamma) and Indian variants. Suitable for use as a capture or detection antibody in ELISA assays. Horseradish peroxidase (HRP) and Biotin conjugated antibody also available. Antibody recognizes the Omicron variant.
SARS-CoV-2 (N501Y Mutant) Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
UNITED KINGDOM (ALPHA) VARIANT SARS-CoV-2 (N501Y mutant) spike subunit 1 (S1) receptor binding domain (RBD) is a recombinant antigen manufactured in HEK293 cells to high purity. This antigen contains N501Y amino acid change relative to the Wuhan-Hu-1 isolate. The N501Y mutation has been reported to increase binding affinity to human ACE2. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Human IgG1 Anti-SARS-CoV-2 Spike NTD Antibody, Chimeric mAb (AM121)
Human IgG1 anti-SARS-CoV-2 spike NTD neutralizing antibody is a chimeric mAb combining the constant domains of the human IgG1 molecule with mouse variable regions. This antibody recognizes the SARS-CoV-2 N-terminal domain (NTD).
SARS-CoV-2 Spike N-Terminal Domain (NTD), His-Tag (HEK293)
Recombinant SARS-CoV-2 Spike protein N-terminal domain (NTD). This domain shows the lowest sequence ID compared to SARS-CoV Spike protein. The protein is produced in HEK293 cells and purified from culture supernatant by affinity chromatography. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Human IgA Anti-SARS-CoV-2 Spike Antibody (A60H)
Anti-SARS-CoV-2 Spike antibody (A60H) is a recombinant monoclonal antibody that recognizes the SARS-CoV and SARS-CoV-2 Spike glycoprotein, the causative agent of COVID-19. Antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity at the Receptor Binding Domain (RBD) in the S1 subunit of the Spike protein.
SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag (HEK293)
SARS-CoV-2 (formerly known as Novel Coronavirus 2019-nCoV) Spike Glycoprotein (S1) is a recombinant antigen which contains amino acids 1-674 of subunit 1. Spike S1 protein is manufactured in HEK293 mammalian cells to obtain more authentic post-translational modifications, compared to other expression systems. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. Horseradish peroxidase (HRP) conjugated protein is also available ready for use in various immunochemical assays including Western blotting, immunohistochemistry, ELISA applications and double‐antigen bridging assays (DABA).
SARS-CoV-2 Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
SARS-CoV-2 Spike S1 RBD is a recombinant receptor-binding domain antigen, expressed in HEK293 cells and purified from culture supernatant with a His-tag to These proteins can be used as diagnostic standard antigens, targets of neutralizing antibodies and in the development of antibodies to detect SARS-CoV-2 in patients.
SARS-CoV-2 Spike Glycoprotein (Trimeric), His-Tag (CHO)
SARS-CoV-2 trimeric spike glycoprotein is manufactured in CHO cells to high yield and purity. Protein has proline substitutions at residues 986 and 987, a GSAS substitution at the furin cleavage site (residues 682–685), and a C-terminal His-tag. HRP conjugated protein also available. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Rabbit IgG Anti-SARS-CoV-2 Spike (S1) Polyclonal Antibody
SARS-CoV-2 Spike (S1) polyclonal antibody recognizes the SARS-CoV-2 Spike glycoprotein subunit 1. Antibody is suitable for Western blot, IF and ELISA; it does not cross-react in ELISA with HCoV-229E full-length spike protein (REC31880). SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (Full-Length), His-Tag (CHO)
Recombinant full-length SARS-CoV-2 spike glycoprotein, manufactured in Chinese hamster ovary (CHO) cells to high yield and purity. The furin cleavage site (amino acids 682-685) has been mutated from RRAR to SRAS and the transmembrane domain and intravirion part replaced with a glycine-serine linker and a His-tag. Horseradish peroxidase conjugated protein also available. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Rabbit IgG Anti-SARS-CoV-2 Spike (S2) Polyclonal Antibody
SARS-CoV-2 Spike (S2) polyclonal antibody is an antibody that recognizes the SARS-CoV-2 Spike glycoprotein subunit 2. Antibody is suitable for use in Western blot and ELISA and does not cross-react in ELISA with HCoV-229E full-length spike protein (REC31880). SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike N-Terminal Domain (NTD), Sheep Fc-Tag (HEK293)
Recombinant SARS-CoV-2 Spike protein N-terminal domain (NTD) is manufactured in HEK293 cells and purified to greater than 95% purity from culture supernatant with a sheep Fc-tag. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoproteins (S2), Sheep Fc-Tag (HEK293/CHO Cell Duo Pack)
This SARS-CoV-2 Spike Duo Pack contains recombinant subunit 2 (S2) proteins manufactured in both HEK293 and CHO cells, for comparative analysis of expression host-cell differences, including post-translational modifications (PTMs) such as glycosylation. These proteins can be used in conjunction to investigate glycan-dependent differences in ACE2 binding affinities and susceptibility to neutralization by monoclonal antibodies or polyclonal sera.
SARS-CoV-2 Spike Glycoproteins (S1), Sheep Fc-Tag (HEK293/CHO Cell Duo Pack)
This SARS-CoV-2 Spike Duo Pack contains recombinant subunit 1 (S1) proteins manufactured in both HEK293 and CHO cells, for comparative analysis of expression host-cell differences, including post-translational modifications (PTMs) such as glycosylation. These proteins can be used in conjunction to investigate glycan-dependent differences in ACE2 binding affinities and susceptibility to neutralization by monoclonal antibodies or polyclonal sera.
SARS-CoV-2 (B.1.1.7 + E484K) Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293)
UNITED KINGDOM (ALPHA) VARIANT Pre-fusion stabilized SARS-CoV-2 Spike protein of the 'New Kent'; variant B.1.1.7 containing amino acid change E484K (in addition to 69-70del, Y144del, N501Y, A570D, P681H, T716I, S982A, D1118H). SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. Lineage B.1.1.7 (Variant of Concern 202012/01) is correlated with a significant increase in the rate of COVID-19 infection in the UK.
SARS-CoV-2 (B.1.1.7) Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293)
UNITED KINGDOM (ALPHA) VARIANT SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. Lineage B.1.1.7 (Variant of Concern 202012/01) is correlated with a significant increase in the rate of COVID-19 infection in the UK and includes amino acid substitutions 69-70del, Y144del, N501Y, A570D, P681H, T716I, S982A, D1118H relative to the prototypic Wuhan-Hu-1 strain.
Human CD147 (BSG) Recombinant Protein, His-Tag (HEK293)
Recombinant human basigin (BSG, CD147) produced in HEK293 cells and purified from culture supernatant. There is evidence that this protein can serve as an alternative entry receptor for SARS-CoV-2. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.1.7) Spike Glycoprotein (Full-Length), His-Tag (HEK293)
UNITED KINGDOM (ALPHA) VARIANT SARS-CoV-2 Spike protein that contains all amino acid changes of the “UK variant” B.1.1.7 of SARS-CoV-2: 69-70del, Y144del, N501Y, A570D, P681H, T716I, S982A, D1118H relative to Wuhan-Hu-1. This construct has a functional furin cleavage site. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293)
SARS-CoV-2 Stabilized Spike (full-length) is a recombinant antigen which contains 6 mutations in S2 which stabilises the protein as a pre-fusion trimer. The protein was produced according to Hsieh et al. in HEK293 cells and purified from culture supernatant by affinity chromatography. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS Coronavirus Spike Glycoprotein (S1), His-Tag (HEK293)
SARS Coronavirus Spike Glycoprotein (S1) is a recombinant antigen which contains amino acids 1-666 of S1 subunit. It is manufactured in mammalian HEK293 cells with
SARS-CoV-2 Spike Glycoprotein (S2), Sheep Fc-Tag (HEK293)
SARS-CoV-2 (formerly known as Novel Coronavirus 2019-nCoV) Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike subunit 2 protein, amino acids 685-1211. Spike S2 protein is manufactured in HEK293 mammalian cells to obtain more authentic post-translational modifications, compared to other expression systems. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. Horseradish peroxidase (HRP) conjugated protein is also available ready for use in various immunochemical assays including Western blotting, immunohistochemistry, ELISA applications and double‐antigen bridging assays (DABA).
SARS-CoV-2 Spike Glycoprotein (S2), Sheep Fc-Tag (CHO)
SARS-CoV-2 (formerly known as Novel Coronavirus 2019-nCoV) Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike subunit 2 protein, amino acids 685-1211. Spike S2 protein is manufactured in CHO mammalian cells to SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag (CHO)
SARS-CoV-2 (formerly known as Novel Coronavirus 2019-nCoV) Spike Glycoprotein (S1) is a recombinant antigen which contains amino acids 1-674 of subunit 1. Spike S1 protein is manufactured in CHO mammalian cells to SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S2) (aa 1000-1200), His-Tag (E. coli)
SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen manufactured in E. coli and containing the Spike subunit 2 immunodominant region (amino acids 1000 to 1200). SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S2) (aa 800-1000), His-Tag (E. coli)
SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen manufactured in E. coli and containing the Spike subunit 2 immunodominant region (amino acids 800 to 1000). SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S2), His-Tag (Insect Cells)
SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike protein amino acids 685-1211 of subunit 2. Spike S2 protein is manufactured to high yield and purity using the Native Antigens baculovirus-insect cell platform. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S1), His-Tag (Insect Cells)
SARS-CoV-2 (formerly known as Novel Coronavirus 2019-nCoV) Spike Glycoprotein (S1) is a recombinant antigen which contains the Spike protein amino acids 1-674 of subunit 1. Spike S1 protein is manufactured to high yield and purity using the Native Antigens baculovirus-insect cell platform. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.617.2; AY.1, AY.2, AY.3) Stabilized Spike Glycoprotein (Trimeric), His-Strep-Tag (HEK293)
INDIAN (DELTA) VARIANT SARS-CoV-2 (B.1.617.2; AY.1, AY.2, AY.3) stabilized Spike from the Indian (Delta) variant. Contains T19R, T95I, G142D, E156G, del157-158, W258L, N417K, L452R, T478K, D614G, P681R, D950N mutations. The protein was produced in HEK293 cells and purified from culture supernatant. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.617.2) Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
INDIAN (DELTA) VARIANT SARS-CoV-2 (B.1.617.2) RBD mutant from the Delta variant. Contains amino acid changes L452R, T478K relative to Wuhan Hu-1. The protein was produced in HEK293 cells and purified from culture supernatant. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.617.1) Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
KERALA (KAPPA) VARIANT SARS-CoV-2 (B.1.617.1) RBD mutant from the Kerala variant. Contains amino acid changes E484Q, L452R relative to Wuhan Hu-1. The protein was produced in HEK293 cells and purified from culture supernatant. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.351) Stabilized Spike Glycoprotein (Trimeric), His-Strep-Tag (HEK293)
SOUTH AFRICAN (BETA) VARIANT SARS-CoV-2 (B.1.351) stabilized spike glycoprotein, from the South Africa variant. It contains amino acid changes L18F, D80A, D215G, del242-244, K417N, E484K, N501Y, D614G, and A701V, relative to Wuhan-Hu-1. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.351/501Y.V2) Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
SOUTH AFRICAN (BETA) VARIANT SARS-CoV-2 spike receptor binding domain (RBD) from South African variant. Contains amino acid changes K417N, E484K, N501Y relative to Wuhan Hu-1. The protein was produced in HEK293 cells and purified from culture supernatant. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 (B.1.351/501.V2) Stabilized Spike Glycoprotein (Full-Length), His-Strep-Tag (HEK293)
SOUTH AFRICAN (BETA) VARIANT SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease. The B.1.351/501.V2 variant, also known as 501.V2, 20H/501Y.V2 (formerly 20C/501Y.V2), was first detected in South Africa and includes the amino acid substitutions D80A, D215G, K417N, E484K, N501Y and A701V relative to the prototypic Wuhan-Hu-1 strain.
Human Coronavirus NL63 Spike Glycoprotein (S1), His-Tag (HEK293)
Human coronavirus NL63 spike glycoprotein is a recombinant HCoV-NL63 spike subunit 1 protein (S1), with C-terminus His-tag. This antigen is manufactured in HEK293 cells, with
Human Coronavirus NL63 Spike Glycoprotein (Full-Length), Sheep Fc-Tag (HEK293)
Human coronavirus NL63 full-length spike glycoprotein is a recombinant HCoV-NL63 spike protein, with sheep Fc-tag. This antigen is manufactured in HEK293 cells, with greater than % purity.
SARS-CoV-2 Spike-E-M Mosaic Protein, His-Tag (E. coli)
SARS-CoV-2 Spike-E-M Mosaic protein is a recombinant antigen manufactured in E. coli with greater than 95% purity, and containing the Spike (S), Envelope (E) and Membrane (M) immunodominant regions. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Purified Viral Lysate
This virus was isolated from a patient with a respiratory illness who had returned from travel to the affected region of China and developed COVID-19 in January 2020 in Washington, USA. The virus is purified using sucrose density gradient ultracentrifugation, disrupted in the presence of detergent and heat inactivated. Whole virus lysate antigen can be used for the development of diagnostic tests to detect virus antibodies in human serum or plasma. It can also be used to test anti-viral compounds, develop new vaccines, and perform basic research as well as serve as a diagnostic reference for the public health community. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Human Coronavirus 229E Nucleoprotein, His-Tag (E. coli)
Human coronavirus 229E nucleoprotein is a recombinant HCoV-229E nucleocapsid protein manufactured in E. coli, with C-terminal His-tag.
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